• If the users have no data of 3’UTR of mRNA of pathogen. They can provide DNA, RNA, or protein sequences of target protein of pathogen for prediction of potential human miRNA. (We recommend providing the DNA/RNA sequence for accuracy)
• We have observed that in most of the cases, human miRNA that can interact with 3’UTR of pathogen mRNA or inhibit the protein/gene expression of pathogen, have also shown presence of seed sequence of miRNA in the cDNA sequence of respective protein.
• The predicted human miRNA can be further used for computational biology, bioinformatics, or wet lab experiments and analysis as well as a therapeutic agent against that specific pathogen.
• If we upregulate the predicted human miRNA or use miRNA mimic against pathogens, it will significantly diminish their growth. Ultimately, it may help to control the pathogenic disease.
• Before clinical trials, the predicted human miRNA must be experimentally validated.
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