• For in silico validation of predicted human miRNA, users can use miRNA-Validator tool.
• If users have details of downregulated miRNA during specific pathogenic infections (such as HIV, influenza, etc.), they can use this tool. Users can provide the list of downregulated miRNAs as input along with the 3’UTR sequence of mRNA or protein/DNA/mRNA sequence as input. (We recommend providing the DNA/RNA sequence for accuracy)
• This will help to identify and in silico validation of more potential human miRNA that can be further used as potential therapeutics.
• To obtain the results, the user must submit:
o Sequence of 3’UTR of mRNA or DNA/RNA/protein sequence of surface protein/pathogenesis-associated protein of pathogen.
o List of human miRNAs that are reported as downregulated during pathogenic disease.
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